Yb(OTf)3-catalyzed cyclization of an N-silylenamine with 2-methylene-1,3-cyclohexanedione to afford a 7,8-dihydroquinolin-5(6H)-one derivative and its application to the one-pot conversion to a 2,3,5-trisubstituted quinoline derivative

Norio Sakai, Daisuke Aoki, Toshihiro Hamajima, Takeo Konakahara

研究成果: Article査読

41 被引用数 (Scopus)

抄録

A catalytic amount of ytterbium triflate (Yb(OTf)3) promotes the cyclization of an N-silylenamine with in situ generated 2-methylene-1,3- cyclohexanedione and 2-methylenecyclohexanone to produce the corresponding 2,3-disubstituted 7,8-dihydroquinolin-5-one and 5,6,7,8-tetrahydroquinolin-5-one in moderate to good yields. A one-pot conversion of 7,8-dihydroquinolin-5-one to the quinoline derivative also proceeded in good yield.

本文言語English
ページ(範囲)1261-1265
ページ数5
ジャーナルTetrahedron Letters
47
8
DOI
出版ステータスPublished - 20 2月 2006

フィンガープリント

「Yb(OTf)3-catalyzed cyclization of an N-silylenamine with 2-methylene-1,3-cyclohexanedione to afford a 7,8-dihydroquinolin-5(6H)-one derivative and its application to the one-pot conversion to a 2,3,5-trisubstituted quinoline derivative」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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