Tripodal thiol-derivatives as a functional interface monolayer for immobilization of biomolecules

Toshiya Sakata, Sumio Maruyama, Hidenori Otsuka, Yuji Miyahara

研究成果: Conference contribution査読

抄録

We designed interface molecules for immobilization of biomolecules on solid substrate and applied it to genetic field effect transistors. We have been investigating a new approach to realize a potentiometric detection for DNA chips. The concept of a genetic field effect transistor has been proposed for improving precision, standardization and miniaturization of a DNA chip system. We have designed and synthesized tripodal thiol-derivatives for stable immobilization of oligonucleotide probes on a gold surface. The genetic FET platform combined with the new interface molecule is suitable for a simple, accurate and inexpensive system for SNP typing In clinical diagnostics. α 2005 IEEE.

本文言語English
ホスト出版物のタイトル2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
ページ215-218
ページ数4
DOI
出版ステータスPublished - 2005
イベント2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology - Oahu, HI, United States
継続期間: 12 5月 200515 5月 2005

出版物シリーズ

名前2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
2005

Conference

Conference2005 3rd IEEE/EMBS Special Topic Conference on Microtechnology in Medicine and Biology
国/地域United States
CityOahu, HI
Period12/05/0515/05/05

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