Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi; Naokazu Idota; Jun Kobayashi; Teruo Okano

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi, Naokazu Idota, Jun Kobayashi, Teruo Okano

マテリアル創成工学科

研究成果: Paper › 査読

抄録

We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

本文言語	English
ページ	5067-5068
ページ数	2
出版ステータス	Published - 1 12月 2006
イベント	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan 継続期間: 20 9月 2006 → 22 9月 2006

Conference

Conference	55th Society of Polymer Science Japan Symposium on Macromolecules
国/地域	Japan
City	Toyama
Period	20/09/06 → 22/09/06

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Link to publication in Scopus

引用スタイル

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title = "Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules",

abstract = "We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.",

keywords = "Microfluidics, Nano-interfaces, Separation, Thermoresponse, Velving function",

author = "Akihiko Kikuchi and Naokazu Idota and Jun Kobayashi and Teruo Okano",

year = "2006",

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T1 - Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

AU - Kikuchi, Akihiko

AU - Idota, Naokazu

AU - Kobayashi, Jun

AU - Okano, Teruo

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

AB - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

KW - Microfluidics

KW - Nano-interfaces

KW - Separation

KW - Thermoresponse

KW - Velving function

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M3 - Paper

AN - SCOPUS:33846141532

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T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

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