11B NMR/MRI Sensing of Copper(II) Ions In Vitro by the Decomposition of a Hybrid Compound of a nido-o-Carborane and a Metal Chelator

Tomohiro Tanaka, Rikita Araki, Takaomi Saido, Ryo Abe, Shin Aoki

研究成果: Article査読

6 被引用数 (Scopus)

抄録

Cu2+is closely correlated with certain types of physiological and pathological events. Therefore, the development of a noninvasive methodology for detecting Cu2+is important for understanding its biological role and relationship with disease. Herein, we report on the development of a Cu2+-specific11B NMR/MRI probe that contains a chelator unit, TriMEDA. The method is based on the rapid complete deboronation of nido-o-carborane by Cu2+under physiological conditions.

本文言語English
ページ(範囲)3330-3337
ページ数8
ジャーナルEuropean Journal of Inorganic Chemistry
2016
20
DOI
出版ステータスPublished - 7月 2016

フィンガープリント

11B NMR/MRI Sensing of Copper(II) Ions In Vitro by the Decomposition of a Hybrid Compound of a nido-o-Carborane and a Metal Chelator」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

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