Screening of circulating tumor cells in tumor-bearing mouse blood by a deterministic lateral displacement micro fluidic device

Hiromasa Okano, Keiki Suyama, Shinya Ariyasu, Toshihiro Suzuki, Ryo Abe, Shin Aoki, Masanori Hayase

研究成果: Conference contribution査読

1 被引用数 (Scopus)

抄録

Enrichment of CTCs in blood of tumor-bearing mice using a microfiuidic device by the deterministic lateral displacement method was demonstrated. Micro-posts structure for size based sorting was fabricated on Si substrate, and the screening for CTC detection was performed. Tumor-bearing mouse were prepared by inoculating tumor cells with GFP (green fluorescent protein) expression, and the CTCs were distinguished by its fluorescence. Before the sorting, no CTCs were detected in 1.5 million cells, while 12 CTCs were detected in 2.4 × 10 4 cells of larger cell section after the screening.

本文言語English
ホスト出版物のタイトル17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
出版社Chemical and Biological Microsystems Society
ページ1021-1023
ページ数3
ISBN(印刷版)9781632666246
出版ステータスPublished - 1 1月 2013
イベント17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
継続期間: 27 10月 201331 10月 2013

出版物シリーズ

名前17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
2

Conference

Conference17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
国/地域Germany
CityFreiburg
Period27/10/1331/10/13

フィンガープリント

「Screening of circulating tumor cells in tumor-bearing mouse blood by a deterministic lateral displacement micro fluidic device」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル