TY - CONF
T1 - Preparation of high-density thermo-responsive polymer grafted surfaces and their application in novel aqueous chromatography column packed materials
AU - Mizutami, Aya
AU - Kikuchi, Akihiko
AU - Idota, Naokazu
AU - Kobayashi, Jun
AU - Sakai, Kiyotaka
AU - Kanazawa, Hideko
AU - Okano, Temo
PY - 2005
Y1 - 2005
N2 - In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.
AB - In the present research, thermoresponsive surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) on silica-based chromatography column packing materials. Prepared surfaces were analyzed in terms of surface elemental analyses and amount of the grafted polymers increased with increasing reaction time, indicating that reaction proceeds in living fashioa Thermoresponsive surface property alteration was also analyzed in hydrophobic chromatography of hydrophobic bioactive molecules under aqueous mobile phase.
KW - Chromatography matrices
KW - High-density polymer grafted surfaces
KW - Poly(N-isopropylacrylamide)
KW - Surface-initiated atom transfer radical polymerization
KW - Thermoresponsive polymer
UR - http://www.scopus.com/inward/record.url?scp=33645637231&partnerID=8YFLogxK
M3 - Paper
AN - SCOPUS:33645637231
SP - 2256
T2 - 54th SPSJ Annual Meeting 2005
Y2 - 25 May 2005 through 27 May 2005
ER -