Over 1000 nm near-infrared multispectral imaging system for laparoscopic in vivo imaging

Toshihiro Takamatsu, Yuichi Kitagawa, Kohei Akimoto, Ren Iwanami, Yuto Endo, Kenji Takashima, Kyohei Okubo, Masakazu Umezawa, Takeshi Kuwata, Daiki Sato, Tomohiro Kadota, Tomohiro Mitsui, Hiroaki Ikematsu, Hideo Yokota, Kohei Soga, Hiroshi Takemura

研究成果: Article査読

1 被引用数 (Scopus)

抄録

In this study, a laparoscopic imaging device and a light source able to select wavelengths by bandpass filters were developed to perform multispectral imaging (MSI) using over 1000 nm near-infrared (OTN-NIR) on regions under a laparoscope. Subsequently, MSI (wavelengths: 1000– 1400 nm) was performed using the built device on nine live mice before and after tumor implantation. The normal and tumor pixels captured within the mice were used as teaching data sets, and the tumor-implanted mice data were classified using a neural network applied following a leaveone-out cross-validation procedure. The system provided a specificity of 89.5%, a sensitivity of 53.5%, and an accuracy of 87.8% for subcutaneous tumor discrimination. Aggregated true-positive (TP) pixels were confirmed in all tumor-implanted mice, which indicated that the laparoscopic OTN-NIR MSI could potentially be applied in vivo for classifying target lesions such as cancer in deep tissues.

本文言語English
論文番号2649
ジャーナルSensors
21
8
DOI
出版ステータスPublished - 2 4月 2021

フィンガープリント

「Over 1000 nm near-infrared multispectral imaging system for laparoscopic in vivo imaging」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル