NHC-catalyzed green synthesis of functionalized chromones: DFT mechanistic insights and: In vitro activities in cancer cells

Keyphrases

• Cancer Cells 100%
• In Cancer 100%
• Mechanistic Insight 100%
• Nitriles 100%
• Density Functional Theory 100%
• Chromone 100%
• In Vitro Activity 100%
• N-heterocyclic Carbenes 100%
• Green Synthesis 100%
• IC50 Value 66%
• HeLa S3 66%
• Intramolecular Hydroacylation 66%
• Breslow Intermediate 66%
• Small Molecules 33%
• HeLa S3 Cells 33%
• Commercially Available 33%
• Ionic Liquid 33%
• Amines 33%
• A549 33%
• Anticancer Drugs 33%
• Anticancer Activity 33%
• Morphological Changes 33%
• Efficient Synthesis 33%
• Imines 33%
• Carbon-carbon Bond 33%
• Morphology Control 33%
• Microwave Condition 33%
• Environmental Friendliness 33%
• Colony Formation 33%
• Salicylaldehyde 33%
• Chemical Reactivity 33%
• Thiazolium 33%
• Tautomerism 33%
• Imine Intermediates 33%
• Amine Functionalization 33%
• Acyl Anions 33%
• Short Reaction Time 33%
• Activated Alkynes 33%

Chemistry

• Density Functional Theory 100%
• N-Heterocyclic Carbene 100%
• Scanning Voltage Microscopy 100%
• Chromone 100%
• Nitrile 75%
• IC50 50%
• Imine 50%
• formation 50%
• Environmental Friendliness 25%
• Ionic Liquid 25%
• Tautomerization 25%
• Antineoplastic Agent 25%
• Salicylaldehyde 25%
• Tautomer 25%
• Chemical Reactivity 25%
• Alkyne 25%