@inproceedings{a2b1be871d0142f78610c8c5fc3798a7,
title = "LABEL-FREE DIELECTROPHORETIC SEPARATION OF CANCER CELLS BY DRUG RESISTANCE",
abstract = "In this study, we firstly succeeded the label-free separation of normal and drug resistance (DR) cells by a novel dielectrophoretic (DEP) device that utilizes two-step separation processes. DEP separation performance based on dielectric properties can be improved by size-based sorting before the separation. Our experiments shows that DR cells differ cytoplasm conductivity from normal cells and that the two-step approach implemented with size-sorting with 1 μm resolution increase the separation rate by 40\%.",
keywords = "Cancer cell, Dielectrophoresis, Drug resistance, Electrorotation, Label-free separation",
author = "Kazuma Yoda and Yuto Sasaki and Ken Yamamoto and Yoshiyasu Ichikawa and Masahiro Motosuke",
note = "Funding Information: A part of this study was financially supported by Grant-in-Aid for Scientific Research (B) No. 19H02084, supported by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. A Part of microfabrication was performed in Center for Nano Lithography \& Analysis, The University of Tokyo. Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",
year = "2021",
language = "English",
series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "249--250",
booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}