TY - CONF
T1 - Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains
AU - Mizutani, Aya
AU - Kikuchi, Akihiko
AU - Kobayashi, Jun
AU - Akiyama, Yoshikatsu
AU - Kanazawa, Hideko
AU - Okano, Teruo
PY - 2006
Y1 - 2006
N2 - In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.
AB - In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.
KW - Cell adhesion
KW - High-density polymer grafted surfaces
KW - Poly(N-isopropylacrylamide)
KW - Surface-initiated atom transfer radical polymerization
KW - Thermoresponsive polymer
UR - http://www.scopus.com/inward/record.url?scp=33749821291&partnerID=8YFLogxK
M3 - Paper
AN - SCOPUS:33749821291
SP - 2037
T2 - 55th SPSJ Annual Meeting
Y2 - 24 May 2006 through 26 May 2006
ER -