Effects of graft densities and chain lengths on separation of bioactive compounds on nanolayered thermoresponsive polymer grafted surfaces

Kenichi Nagase; Jun Kobayashi; Akihiko Kikuchi; Hideko Kanazawa; Teruo Okano

Effects of graft densities and chain lengths on separation of bioactive compounds on nanolayered thermoresponsive polymer grafted surfaces

Kenichi Nagase, Jun Kobayashi, Akihiko Kikuchi, Hideko Kanazawa, Teruo Okano

マテリアル創成工学科

研究成果: Paper › 査読

抄録

We introduced poly(N-isopropylacrylamide) (PIPAAm) brush onto silica bead surfaces with various graft densities and chain lengths by surface-initiated atom transfer radical polymerization (ATRP) technique. Ulitilizing these PIPAAm-grafted beads as chromatographic column matrixes, temperature-dependent elution profiles of steroids were examined at various temperature. Chromatograms with narrow peak widths were obtained by decreasing graft density of PIPAAm. Consequently, the graft density of PIPAAm affects the separation efficiency of PIPAAm grafted columns.

本文言語	English
ページ数	1
出版ステータス	Published - 19 10月 2006
イベント	55th SPSJ Annual Meeting - Nagoya, Japan 継続期間: 24 5月 2006 → 26 5月 2006

Conference

Conference	55th SPSJ Annual Meeting
国/地域	Japan
City	Nagoya
Period	24/05/06 → 26/05/06

他のファイルとリンク

Link to publication in Scopus

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「Effects of graft densities and chain lengths on separation of bioactive compounds on nanolayered thermoresponsive polymer grafted surfaces」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル

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title = "Effects of graft densities and chain lengths on separation of bioactive compounds on nanolayered thermoresponsive polymer grafted surfaces",

abstract = "We introduced poly(N-isopropylacrylamide) (PIPAAm) brush onto silica bead surfaces with various graft densities and chain lengths by surface-initiated atom transfer radical polymerization (ATRP) technique. Ulitilizing these PIPAAm-grafted beads as chromatographic column matrixes, temperature-dependent elution profiles of steroids were examined at various temperature. Chromatograms with narrow peak widths were obtained by decreasing graft density of PIPAAm. Consequently, the graft density of PIPAAm affects the separation efficiency of PIPAAm grafted columns.",

keywords = "Bioactive compounds, Chromatography, Graft density, Living radical polymerization, Thermoresponsive surfaces",

author = "Kenichi Nagase and Jun Kobayashi and Akihiko Kikuchi and Hideko Kanazawa and Teruo Okano",

year = "2006",

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T1 - Effects of graft densities and chain lengths on separation of bioactive compounds on nanolayered thermoresponsive polymer grafted surfaces

AU - Nagase, Kenichi

AU - Kobayashi, Jun

AU - Kikuchi, Akihiko

AU - Kanazawa, Hideko

AU - Okano, Teruo

PY - 2006/10/19

Y1 - 2006/10/19

N2 - We introduced poly(N-isopropylacrylamide) (PIPAAm) brush onto silica bead surfaces with various graft densities and chain lengths by surface-initiated atom transfer radical polymerization (ATRP) technique. Ulitilizing these PIPAAm-grafted beads as chromatographic column matrixes, temperature-dependent elution profiles of steroids were examined at various temperature. Chromatograms with narrow peak widths were obtained by decreasing graft density of PIPAAm. Consequently, the graft density of PIPAAm affects the separation efficiency of PIPAAm grafted columns.

AB - We introduced poly(N-isopropylacrylamide) (PIPAAm) brush onto silica bead surfaces with various graft densities and chain lengths by surface-initiated atom transfer radical polymerization (ATRP) technique. Ulitilizing these PIPAAm-grafted beads as chromatographic column matrixes, temperature-dependent elution profiles of steroids were examined at various temperature. Chromatograms with narrow peak widths were obtained by decreasing graft density of PIPAAm. Consequently, the graft density of PIPAAm affects the separation efficiency of PIPAAm grafted columns.

KW - Bioactive compounds

KW - Chromatography

KW - Graft density

KW - Living radical polymerization

KW - Thermoresponsive surfaces

UR - http://www.scopus.com/inward/record.url?scp=33749830946&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33749830946

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -