Cu(OTf)₂ catalyzed three component strategy for the synthesis of thienopyridine containing spirooxindoles and their cytotoxic evaluation

Keyphrases

• Thienopyridines 100%
• Cytotoxic Evaluation 100%
• Spirooxindole 100%
• Cu(OTf)2-catalyzed 100%
• Binding Energy 33%
• Room Temperature 33%
• IC50 33%
• Cytotoxicity 33%
• Caspase-3 33%
• DNA Laddering 33%
• Excellent Yields 33%
• Molecular Docking 33%
• Three-component Reaction 33%
• Isatin 33%
• Temperature Protocol 33%
• Copper Catalysis 33%
• Malononitrile 33%

Chemistry

• Thienopyridine 100%
• Spirooxindole 100%
• Binding Energy 33%
• Ambient Reaction Temperature 33%
• Deoxyribonucleic Acid 33%
• IC50 33%
• Isatin 33%
• Malononitrile 33%
• formation 33%