Concise and versatile synthesis of sulfoquinovosyl acyl glycerol derivatives for biological applications

Tomohiro Tanaka, Yasuhiro Sawamoto, Shin Aoki

研究成果: Article査読

2 被引用数 (Scopus)

抄録

Sulfoquinovosyl acylpropanediol (SQAP), a chemically modified analogue of sulfoquinovosyl acylglycerol (SQAG) that occurs in sea algae, has been reported to show a variety of biological activities, including accumulation in tumor cells and the inhibition of tumor cell growth. We report herein on a new concise and versatile synthesis of SQAP itself and derivatives bearing iodoaryl groups and boronclusters. This method should be useful for the design and synthesis of SQAG/SQAP derivatives for diagnosis and the treatment of cancer and related diseases.

本文言語English
ページ(範囲)566-572
ページ数7
ジャーナルChemical and Pharmaceutical Bulletin
65
6
DOI
出版ステータスPublished - 2017

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