Toward the multi-scale simulation for a human body using the next-generation supercomputer

Yoichiro Matsumoto, Satoshi Ii, Seiji Shiozaki, Kazuyasu Sugiyama, Shu Takagi

Research output: Contribution to journalConference article

2 Citations (Scopus)

Abstract

We have developed novel numerical methods for fluid-structure and fluid-membrane interaction problems. The basic equation set is formulated in a full Eulerian framework. The method is based on the finite difference volume-of-fluid scheme with fractional step algorithm. It is validated through a numerical solution to a deformable vesicle problem, and applied to blood flows including red blood cells (RBCs) and platelets. Further, to gain insight into the mechanism of thrombus formation, a stochastic Monte Carlo model to describe the platelet-vessel wall interaction is incorporated into the Eulerian method. The effect of the RBCs on the platelet motion is discussed.

Original languageEnglish
Pages (from-to)193-200
Number of pages8
JournalProcedia IUTAM
Volume10
DOIs
Publication statusPublished - 1 Jan 2014
Event23rd International Congress of Theoretical and Applied Mechanics: Mechanics for the World, ICTAM 2012 - Beijing, China
Duration: 19 Aug 201224 Aug 2012

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Keywords

  • Blood flow
  • Eulerian method
  • Fluid-structure interaction
  • Stochastic Monte Carlo method

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