Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi; Naokazu Idota; Jun Kobayashi; Teruo Okano

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Akihiko Kikuchi, Naokazu Idota, Jun Kobayashi, Teruo Okano

Department of Materials Science and Technology

Research output: Contribution to conference › Paper › peer-review

Abstract

We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

Original language	English
Pages	5067-5068
Number of pages	2
Publication status	Published - 1 Dec 2006
Event	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan Duration: 20 Sept 2006 → 22 Sept 2006

Conference

Conference	55th Society of Polymer Science Japan Symposium on Macromolecules
Country/Territory	Japan
City	Toyama
Period	20/09/06 → 22/09/06

Keywords

Microfluidics
Nano-interfaces
Separation
Thermoresponse
Velving function

Cite this

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title = "Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules",

abstract = "We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.",

keywords = "Microfluidics, Nano-interfaces, Separation, Thermoresponse, Velving function",

author = "Akihiko Kikuchi and Naokazu Idota and Jun Kobayashi and Teruo Okano",

year = "2006",

month = dec,

day = "1",

language = "English",

pages = "5067--5068",

note = "55th Society of Polymer Science Japan Symposium on Macromolecules ; Conference date: 20-09-2006 Through 22-09-2006",

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TY - CONF

T1 - Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

AU - Kikuchi, Akihiko

AU - Idota, Naokazu

AU - Kobayashi, Jun

AU - Okano, Teruo

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

AB - We have been extensively investigating nanolayer thermoresponsive polymer-grafted interfaces for biomedical applications. In this report, we briefly summarize recent findings of thermoresponsive nano-interfaces as microfluidic valve systems and interactions of biomolecules on their surfaces. PIPAAm-grafted layers on capillary lumens prepared by electron-beam-irradicated polymerizations induced complete on-off regulations of capillary flows with step temperature regulations. On the other hand, PIPAAm-grafted capillaries prepared by atom transfer radical polymerization, showed differential interactions with biomolecules.

KW - Microfluidics

KW - Nano-interfaces

KW - Separation

KW - Thermoresponse

KW - Velving function

UR - http://www.scopus.com/inward/record.url?scp=33846141532&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33846141532

SP - 5067

EP - 5068

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Thermoresponsive nanolayer-grafted interfaces - Microfluidic valves and interactions with bioactive molecules

Abstract

Conference

Keywords

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