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The gut microbiota-induced kynurenic acid recruits GPR35-positive macrophages to promote experimental encephalitis
Kentaro Miyamoto
, Tomohisa Sujino
, Yosuke Harada
, Hiroshi Ashida
, Yusuke Yoshimatsu
, Yuki Yonemoto
, Yasuhiro Nemoto
, Michio Tomura
, Hassan Melhem
, Jan Hendrik Niess
, Toshihiko Suzuki
, Toru Suzuki
, Shohei Suzuki
, Yuzo Koda
, Ryuichi Okamoto
, Yohei Mikami
, Toshiaki Teratani
, Kenji Tanaka
,
Akihiko Yoshimura
, Toshiro Sato
Takanori Kanai
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Research Institute for Biomedical Sciences
Research output
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Contribution to journal
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Article
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peer-review
25
Citations (Scopus)
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Keyphrases
Macrophages
100%
Kynurenic Acid
100%
Experimental Autoimmune Encephalomyelitis
100%
Gut Microbiota
100%
Encephalitis
100%
GPR35
100%
Immune Response
66%
Small Intestine
33%
CD4+ T Cells
33%
T Helper 17 (Th17)
33%
CX3CR1
33%
Metabolism-related Genes
33%
Spinal Cord
33%
Tryptophan Metabolites
33%
Tryptophan Metabolism
33%
Acid Activation
33%
Microbiota
33%
Synergistic Interaction
33%
Intestinal Cells
33%
Gut Microbiome
33%
Immunology and Microbiology
Macrophage
100%
Experimental Autoimmune Encephalomyelitis
100%
Intestine Flora
100%
Encephalitis
100%
Immune Response
66%
Tryptophan Metabolism
66%
T-Helper Cell
33%
Microflora
33%
Small Intestine
33%
Spinal Cord
33%
Microorganism
33%