Synthesis of cinnolines via Rh(III)-catalysed dehydrogenative C-H/N-H functionalization: Aggregation induced emission and cell imaging

Sivakalai Mayakrishnan, Yuvaraj Arun, Chandrasekar Balachandran, Nobuhiko Emi, Doraiswamy Muralidharan, Paramasivan Thirumalai Perumal

Research output: Contribution to journalArticlepeer-review

59 Citations (Scopus)

Abstract

Rhodium catalysed dehydrogenative C-H/N-H functionalization was developed to construct phthalazino[2,3-a]-/indazolo[1,2-a]cinnolines by reacting N-phenyl phthalazine/indazole with alkynes. The synthesized compounds exhibit prominent fluorescence properties in solid and aggregation states. Their application in cell imaging was investigated using various cancer cell lines.

Original languageEnglish
Pages (from-to)1958-1968
Number of pages11
JournalOrganic and Biomolecular Chemistry
Volume14
Issue number6
DOIs
Publication statusPublished - 2016

Fingerprint

Dive into the research topics of 'Synthesis of cinnolines via Rh(III)-catalysed dehydrogenative C-H/N-H functionalization: Aggregation induced emission and cell imaging'. Together they form a unique fingerprint.

Cite this