Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA120 lectin and the length of the PEG strands

Takao Jinbo; Seiji Takae; Yoshitsugu Akiyama; Hidenori Otsuka; Yuichi Yamasaki; Kazunori Kataoka

Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA₁₂₀ lectin and the length of the PEG strands

Takao Jinbo, Seiji Takae, Yoshitsugu Akiyama, Hidenori Otsuka, Yuichi Yamasaki, Kazunori Kataoka

Research output: Contribution to conference › Paper › peer-review

Abstract

Introduction of ligand onto the surface of non-viral gene vector is an effective strategy to achive in vivo active targeting. In this study, to evaluate the effect of ligand, lactose-installed PEGylated gold nanoparticles were employed as a model. Two types of PEGylated gold nanoparticles were prepared: (_) chain length of PEG with and without lactose on the nonoparticles are same, (ii) chain length of PEG without lactose is shorter than that of PEG with lactose. Then, SPR was used to evaluate the recognition ability of the lactose on the nanoparticle against RCA₁₂₀ lectin.

Original language	English
Pages	2281
Number of pages	1
Publication status	Published - 2005
Event	54th SPSJ Annual Meeting 2005 - Yokohama, Japan Duration: 25 May 2005 → 27 May 2005

Conference

Conference	54th SPSJ Annual Meeting 2005
Country/Territory	Japan
City	Yokohama
Period	25/05/05 → 27/05/05

Keywords

Lactose
Lectin
Length of poly(ethylene glycol)
Poly(ethylene glycol)
Surface plasmon resonance (SPR)

Cite this

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title = "Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA120 lectin and the length of the PEG strands",

abstract = "Introduction of ligand onto the surface of non-viral gene vector is an effective strategy to achive in vivo active targeting. In this study, to evaluate the effect of ligand, lactose-installed PEGylated gold nanoparticles were employed as a model. Two types of PEGylated gold nanoparticles were prepared: (_) chain length of PEG with and without lactose on the nonoparticles are same, (ii) chain length of PEG without lactose is shorter than that of PEG with lactose. Then, SPR was used to evaluate the recognition ability of the lactose on the nanoparticle against RCA120 lectin.",

keywords = "Lactose, Lectin, Length of poly(ethylene glycol), Poly(ethylene glycol), Surface plasmon resonance (SPR)",

author = "Takao Jinbo and Seiji Takae and Yoshitsugu Akiyama and Hidenori Otsuka and Yuichi Yamasaki and Kazunori Kataoka",

year = "2005",

language = "English",

pages = "2281",

note = "54th SPSJ Annual Meeting 2005 ; Conference date: 25-05-2005 Through 27-05-2005",

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Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA₁₂₀ lectin and the length of the PEG strands. / Jinbo, Takao; Takae, Seiji; Akiyama, Yoshitsugu et al.
2005. 2281 Paper presented at 54th SPSJ Annual Meeting 2005, Yokohama, Japan.

Research output: Contribution to conference › Paper › peer-review

TY - CONF

T1 - Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA120 lectin and the length of the PEG strands

AU - Jinbo, Takao

AU - Takae, Seiji

AU - Akiyama, Yoshitsugu

AU - Otsuka, Hidenori

AU - Yamasaki, Yuichi

AU - Kataoka, Kazunori

PY - 2005

Y1 - 2005

N2 - Introduction of ligand onto the surface of non-viral gene vector is an effective strategy to achive in vivo active targeting. In this study, to evaluate the effect of ligand, lactose-installed PEGylated gold nanoparticles were employed as a model. Two types of PEGylated gold nanoparticles were prepared: (_) chain length of PEG with and without lactose on the nonoparticles are same, (ii) chain length of PEG without lactose is shorter than that of PEG with lactose. Then, SPR was used to evaluate the recognition ability of the lactose on the nanoparticle against RCA120 lectin.

AB - Introduction of ligand onto the surface of non-viral gene vector is an effective strategy to achive in vivo active targeting. In this study, to evaluate the effect of ligand, lactose-installed PEGylated gold nanoparticles were employed as a model. Two types of PEGylated gold nanoparticles were prepared: (_) chain length of PEG with and without lactose on the nonoparticles are same, (ii) chain length of PEG without lactose is shorter than that of PEG with lactose. Then, SPR was used to evaluate the recognition ability of the lactose on the nanoparticle against RCA120 lectin.

KW - Lactose

KW - Lectin

KW - Length of poly(ethylene glycol)

KW - Poly(ethylene glycol)

KW - Surface plasmon resonance (SPR)

UR - http://www.scopus.com/inward/record.url?scp=33645636112&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33645636112

SP - 2281

T2 - 54th SPSJ Annual Meeting 2005

Y2 - 25 May 2005 through 27 May 2005

ER -

Surface plasmon resonance study on relationship between recognition ability of lactose-installed PEGylated gold nanoparticles against RCA₁₂₀ lectin and the length of the PEG strands

Abstract

Conference

Keywords

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