Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay

S. Takae; Y. Akiyama; H. Otsuka; T. Nakamura; Y. Nagasaki; K. Kataoka

Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay

S. Takae, Y. Akiyama, H. Otsuka, T. Nakamura, Y. Nagasaki, K. Kataoka

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

The interaction with lectin of poly(ethylene glycol)ylated gold nanoparticles possessing lactose in regulated density was investigated by surface plamon resonance to develop a highly sensitive bioassay system. It was observed that the PEGylated gold particles with higher lactose density increases the binding amount due to the multivalent interaction. A galactose was quantified on the range of 5 ∼ 50μg/mL using the SPR sensor chip with adsorbed gold nanoparticles. It was concluded that the method of amplified SPR sensing by gold nanoparticles can be applied for the qunatification of various low molecular weight compounds.

Original language	English
Title of host publication	Transactions - 7th World Biomaterials Congress
Pages	1386
Number of pages	1
Publication status	Published - 2004
Event	Transactions - 7th World Biomaterials Congress - Sydney, Australia Duration: 17 May 2004 → 21 May 2004

Publication series

Name	Transactions - 7th World Biomaterials Congress

Conference

Conference	Transactions - 7th World Biomaterials Congress
Country/Territory	Australia
City	Sydney
Period	17/05/04 → 21/05/04

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Takae, S., Akiyama, Y., Otsuka, H., Nakamura, T., Nagasaki, Y., & Kataoka, K. (2004). Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay. In Transactions - 7th World Biomaterials Congress (pp. 1386). (Transactions - 7th World Biomaterials Congress).

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title = "Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay",

abstract = "The interaction with lectin of poly(ethylene glycol)ylated gold nanoparticles possessing lactose in regulated density was investigated by surface plamon resonance to develop a highly sensitive bioassay system. It was observed that the PEGylated gold particles with higher lactose density increases the binding amount due to the multivalent interaction. A galactose was quantified on the range of 5 ∼ 50μg/mL using the SPR sensor chip with adsorbed gold nanoparticles. It was concluded that the method of amplified SPR sensing by gold nanoparticles can be applied for the qunatification of various low molecular weight compounds.",

author = "S. Takae and Y. Akiyama and H. Otsuka and T. Nakamura and Y. Nagasaki and K. Kataoka",

year = "2004",

language = "English",

isbn = "1877040193",

series = "Transactions - 7th World Biomaterials Congress",

pages = "1386",

booktitle = "Transactions - 7th World Biomaterials Congress",

note = "Transactions - 7th World Biomaterials Congress ; Conference date: 17-05-2004 Through 21-05-2004",

}

Takae, S, Akiyama, Y , Otsuka, H, Nakamura, T, Nagasaki, Y & Kataoka, K 2004, Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay. in Transactions - 7th World Biomaterials Congress. Transactions - 7th World Biomaterials Congress, pp. 1386, Transactions - 7th World Biomaterials Congress, Sydney, Australia, 17/05/04.

Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay. / Takae, S.; Akiyama, Y.; Otsuka, H. et al.
Transactions - 7th World Biomaterials Congress. 2004. p. 1386 (Transactions - 7th World Biomaterials Congress).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Takae, S.

AU - Akiyama, Y.

AU - Otsuka, H.

AU - Nakamura, T.

AU - Nagasaki, Y.

AU - Kataoka, K.

PY - 2004

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AB - The interaction with lectin of poly(ethylene glycol)ylated gold nanoparticles possessing lactose in regulated density was investigated by surface plamon resonance to develop a highly sensitive bioassay system. It was observed that the PEGylated gold particles with higher lactose density increases the binding amount due to the multivalent interaction. A galactose was quantified on the range of 5 ∼ 50μg/mL using the SPR sensor chip with adsorbed gold nanoparticles. It was concluded that the method of amplified SPR sensing by gold nanoparticles can be applied for the qunatification of various low molecular weight compounds.

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M3 - Conference contribution

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SN - 1877040193

SN - 9781877040191

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SP - 1386

BT - Transactions - 7th World Biomaterials Congress

Y2 - 17 May 2004 through 21 May 2004

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Takae S, Akiyama Y , Otsuka H, Nakamura T, Nagasaki Y, Kataoka K. Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay. In Transactions - 7th World Biomaterials Congress. 2004. p. 1386. (Transactions - 7th World Biomaterials Congress).

Surface Plasmon Resonance (SPR) study on the interaction between lectin and PEGylated gold nanoparticles possessing regulated density of lactose on the surface: Application to the high sensitive bioassay

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