Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides

Chika Yamamoto; Koyo Numata; Minori Suzuki; Suguru Yoshida

doi:10.1039/d4qo01286k

Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides

Chika Yamamoto
, Koyo Numata
, Minori Suzuki
, Suguru Yoshida

Department of Biological Science and Technology

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A regioselective synthesis of trisubstituted pyridazines from tetrazines and alkynyl sulfides is described. Various pyridazines were selectively prepared by the inverse-electron-demand Diels-Alder reaction and subsequent denitrogenation. Good transformability of sulfur substituents allowed us to synthesize a range of pyridazines without regioisomers.

Original language	English
Pages (from-to)	6159-6165
Number of pages	7
Journal	Organic Chemistry Frontiers
Volume	11
Issue number	21
DOIs	https://doi.org/10.1039/d4qo01286k
Publication status	Published - 29 Aug 2024

Access to Document

10.1039/d4qo01286k

Cite this

@article{89dca8b3bc8b45858852a5029cb77bc8,

title = "Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides",

abstract = "A regioselective synthesis of trisubstituted pyridazines from tetrazines and alkynyl sulfides is described. Various pyridazines were selectively prepared by the inverse-electron-demand Diels-Alder reaction and subsequent denitrogenation. Good transformability of sulfur substituents allowed us to synthesize a range of pyridazines without regioisomers.",

author = "Chika Yamamoto and Koyo Numata and Minori Suzuki and Suguru Yoshida",

note = "Publisher Copyright: {\textcopyright} 2024 The Royal Society of Chemistry.",

year = "2024",

month = aug,

day = "29",

doi = "10.1039/d4qo01286k",

language = "English",

volume = "11",

pages = "6159--6165",

journal = "Organic Chemistry Frontiers",

issn = "2052-4110",

publisher = "Royal Society of Chemistry",

number = "21",

}

TY - JOUR

T1 - Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides

AU - Yamamoto, Chika

AU - Numata, Koyo

AU - Suzuki, Minori

AU - Yoshida, Suguru

PY - 2024/8/29

Y1 - 2024/8/29

N2 - A regioselective synthesis of trisubstituted pyridazines from tetrazines and alkynyl sulfides is described. Various pyridazines were selectively prepared by the inverse-electron-demand Diels-Alder reaction and subsequent denitrogenation. Good transformability of sulfur substituents allowed us to synthesize a range of pyridazines without regioisomers.

AB - A regioselective synthesis of trisubstituted pyridazines from tetrazines and alkynyl sulfides is described. Various pyridazines were selectively prepared by the inverse-electron-demand Diels-Alder reaction and subsequent denitrogenation. Good transformability of sulfur substituents allowed us to synthesize a range of pyridazines without regioisomers.

UR - https://www.scopus.com/pages/publications/85204105869

U2 - 10.1039/d4qo01286k

DO - 10.1039/d4qo01286k

M3 - Article

AN - SCOPUS:85204105869

SN - 2052-4110

VL - 11

SP - 6159

EP - 6165

JO - Organic Chemistry Frontiers

JF - Organic Chemistry Frontiers

IS - 21

ER -

Regioselective pyridazine synthesis from tetrazines and alkynyl sulfides

Abstract

Access to Document

Other files and links

Fingerprint

Cite this