Recent topics in total syntheses of natural dimeric naphthoquinone derivatives

Shogo Kamo, Kouji Kuramochi, Kazunori Tsubaki

Research output: Contribution to journalReview article

3 Citations (Scopus)


This digest overviews successful synthetic approaches to natural dimeric 1,4-naphthoquinones. Several natural dimeric 1,4-naphthoquinone derivatives have been isolated from natural sources including plants, bacteria, and fungi. They have diverse structures and attractive biological activities. However, it is difficult to construct the dimeric scaffolds efficiently and selectively, because 1,4-naphthoquinones and their derivatives are highly reactive. Efficient and attractive synthetic methodologies to construct unique dimeric 1,4-naphthoquinone skeletons are reviewed.

Original languageEnglish
Pages (from-to)224-230
Number of pages7
JournalTetrahedron Letters
Issue number3
Publication statusPublished - 17 Jan 2018


  • 1,4-Naphthoquinones
  • Dimerization
  • Natural product
  • Total synthesis

Fingerprint Dive into the research topics of 'Recent topics in total syntheses of natural dimeric naphthoquinone derivatives'. Together they form a unique fingerprint.

  • Cite this