TY - JOUR
T1 - Potassium tert -Butoxide Promoted Intramolecular Mizoroki-Heck-Type Radical Cyclization
T2 - Photoluminescence Properties and Application in Live Cancer-Cell Imaging
AU - Sivaraman, Mahalingam
AU - Mayakrishnan, Sivakalai
AU - Balachandran, Chandrasekar
AU - Aoki, Shin
AU - Maheswari, Narayanan Uma
AU - Perumal, Paramasivan T.
N1 - Funding Information:
M.S. and S.M. thanks the Council of Scientific and Industrial Research, New Delhi, India for research fellowships.CouncilofScienticandIndusial Reseach
Publisher Copyright:
© 2022 EDP Sciences. All rights reserved.
PY - 2022/4/25
Y1 - 2022/4/25
N2 - Privileged indole-fused phenanthridinones were synthesized by an inexpensive potassium tert-butoxide-promoted intramolecular Mizoroki-Heck-type radical cyclization. This method offers high atom-and step-economic C-C bond formation. An array of the synthesized compounds showed good photoluminescence properties, and could be successfully applied as fluorescent bioprobes for imaging of living cancer cells.
AB - Privileged indole-fused phenanthridinones were synthesized by an inexpensive potassium tert-butoxide-promoted intramolecular Mizoroki-Heck-type radical cyclization. This method offers high atom-and step-economic C-C bond formation. An array of the synthesized compounds showed good photoluminescence properties, and could be successfully applied as fluorescent bioprobes for imaging of living cancer cells.
KW - C-H bond functionalization
KW - Mizoroki-Heck reaction
KW - indoles
KW - phenanthridinones
KW - potassium tert- butoxide
KW - transition-metal-free reaction
UR - http://www.scopus.com/inward/record.url?scp=85129298814&partnerID=8YFLogxK
U2 - 10.1055/a-1782-7150
DO - 10.1055/a-1782-7150
M3 - Article
AN - SCOPUS:85129298814
SN - 0936-5214
VL - 33
SP - 785
EP - 790
JO - Synlett
JF - Synlett
IS - 8
ER -