Novel cell sheet carriers using polyion complex gel modified membranes for tissue engineering applications

Zhonglan Tang, Akihiko Kikuchi, Yoshikatsu Akiyama, Teruo Okano

Research output: Contribution to conferencePaper

Abstract

Polyion complexes are prepared consisting of poly(DMAAm-co-AMPS) as the anionic water-soluble polymers and poly(DMAAm-co-ATAC) as the cationic water-soluble polymers. Novel cell sheet carriers are prepared by modifying porous membrane with the polyion complex gels by electron beam irradiated cross-linking and covalent grafting technique. Using the modified membranes, cell sheets can be recovered from temperature-responsive cell culture surfaces and be transferred to new tissue culture polystyrene dishes. This new technique has potential applications for regeneration medicine.

Original languageEnglish
Number of pages1
Publication statusPublished - 19 Oct 2006
Event55th SPSJ Annual Meeting - Nagoya, Japan
Duration: 24 May 200626 May 2006

Conference

Conference55th SPSJ Annual Meeting
CountryJapan
CityNagoya
Period24/05/0626/05/06

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Keywords

  • Cell sheet carrier
  • Electron beam irradiated immobilization
  • Polyion complex gel
  • Regeneration medicine

Cite this

Tang, Z., Kikuchi, A., Akiyama, Y., & Okano, T. (2006). Novel cell sheet carriers using polyion complex gel modified membranes for tissue engineering applications. Paper presented at 55th SPSJ Annual Meeting, Nagoya, Japan.