MAMP-triggered plant immunity mediated by the LysM-receptor kinase CERK1

Yoshitake Desaki, Masaki Kohari, Naoto Shibuya, Hanae Kaku

Research output: Contribution to journalReview article

3 Citations (Scopus)

Abstract

Lysin motif (LysM) receptor-like proteins/kinases (LysM-RLPs/RLKs) are well known to play an important role in the induction of defense or symbiosis signaling through the recognition of carbohydrate ligands in plants. Chitin elicitor receptor kinase 1 (CERK1) is the receptor-like kinase (RLK) essential for chitin-induced defense signaling in Arabidopsis and rice. At/OsCERK1 is also known to be important for peptidoglycan (PGN)-induced defense signaling. To induce chitin and PGN responses, CERK1 forms a receptor complex with corresponding LysM-type receptors such as CEBiP, LYM1/3 or LYP4/6. Furthermore, OsCERK1 in rice also plays a key role in lipopolysaccharide (LPS) signaling, and AtCERK1 in Arabidopsis is involved in unbranched β-glucan signaling. In any case, CERK1 plays a crucial role in the activation of defense signaling by these ligands and is an essential hub-RLK/co-receptor in these systems. After chitin perception, autophosphorylation of the CERK1 kinase domain is essential for inducing immune signaling, and some functionally important phosphorylation sites have been identified. In addition, several CERK1-interacting proteins and their contribution to the downstream signaling have been reported. In particular, phosphorylation of receptor-like cytoplasmic kinases (RLCKs) by CERK1 is important for the activation of chitin signaling. These findings have contributed to our understanding of the early steps of chitin signaling. This review focuses on current knowledge about CERK1-mediated receptor complex formation and subsequent intracellular signaling.

Original languageEnglish
JournalJournal of General Plant Pathology
Volume85
Issue number1
DOIs
Publication statusPublished - 25 Jan 2019

Fingerprint

chitin
phosphotransferases (kinases)
immunity
receptors
peptidoglycans
elicitors
phosphorylation
Arabidopsis
rice
protein phosphorylation
glucans
protein kinases
lipopolysaccharides
symbiosis

Keywords

  • CEBiP
  • CERK1
  • Chitin
  • Lysin motif (LysM)
  • Plant U-box protein (PUB)
  • Receptor-like cytoplasmic kinase (RLCK)

Cite this

Desaki, Yoshitake ; Kohari, Masaki ; Shibuya, Naoto ; Kaku, Hanae. / MAMP-triggered plant immunity mediated by the LysM-receptor kinase CERK1. In: Journal of General Plant Pathology. 2019 ; Vol. 85, No. 1.
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abstract = "Lysin motif (LysM) receptor-like proteins/kinases (LysM-RLPs/RLKs) are well known to play an important role in the induction of defense or symbiosis signaling through the recognition of carbohydrate ligands in plants. Chitin elicitor receptor kinase 1 (CERK1) is the receptor-like kinase (RLK) essential for chitin-induced defense signaling in Arabidopsis and rice. At/OsCERK1 is also known to be important for peptidoglycan (PGN)-induced defense signaling. To induce chitin and PGN responses, CERK1 forms a receptor complex with corresponding LysM-type receptors such as CEBiP, LYM1/3 or LYP4/6. Furthermore, OsCERK1 in rice also plays a key role in lipopolysaccharide (LPS) signaling, and AtCERK1 in Arabidopsis is involved in unbranched β-glucan signaling. In any case, CERK1 plays a crucial role in the activation of defense signaling by these ligands and is an essential hub-RLK/co-receptor in these systems. After chitin perception, autophosphorylation of the CERK1 kinase domain is essential for inducing immune signaling, and some functionally important phosphorylation sites have been identified. In addition, several CERK1-interacting proteins and their contribution to the downstream signaling have been reported. In particular, phosphorylation of receptor-like cytoplasmic kinases (RLCKs) by CERK1 is important for the activation of chitin signaling. These findings have contributed to our understanding of the early steps of chitin signaling. This review focuses on current knowledge about CERK1-mediated receptor complex formation and subsequent intracellular signaling.",
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MAMP-triggered plant immunity mediated by the LysM-receptor kinase CERK1. / Desaki, Yoshitake; Kohari, Masaki; Shibuya, Naoto; Kaku, Hanae.

In: Journal of General Plant Pathology, Vol. 85, No. 1, 25.01.2019.

Research output: Contribution to journalReview article

TY - JOUR

T1 - MAMP-triggered plant immunity mediated by the LysM-receptor kinase CERK1

AU - Desaki, Yoshitake

AU - Kohari, Masaki

AU - Shibuya, Naoto

AU - Kaku, Hanae

PY - 2019/1/25

Y1 - 2019/1/25

N2 - Lysin motif (LysM) receptor-like proteins/kinases (LysM-RLPs/RLKs) are well known to play an important role in the induction of defense or symbiosis signaling through the recognition of carbohydrate ligands in plants. Chitin elicitor receptor kinase 1 (CERK1) is the receptor-like kinase (RLK) essential for chitin-induced defense signaling in Arabidopsis and rice. At/OsCERK1 is also known to be important for peptidoglycan (PGN)-induced defense signaling. To induce chitin and PGN responses, CERK1 forms a receptor complex with corresponding LysM-type receptors such as CEBiP, LYM1/3 or LYP4/6. Furthermore, OsCERK1 in rice also plays a key role in lipopolysaccharide (LPS) signaling, and AtCERK1 in Arabidopsis is involved in unbranched β-glucan signaling. In any case, CERK1 plays a crucial role in the activation of defense signaling by these ligands and is an essential hub-RLK/co-receptor in these systems. After chitin perception, autophosphorylation of the CERK1 kinase domain is essential for inducing immune signaling, and some functionally important phosphorylation sites have been identified. In addition, several CERK1-interacting proteins and their contribution to the downstream signaling have been reported. In particular, phosphorylation of receptor-like cytoplasmic kinases (RLCKs) by CERK1 is important for the activation of chitin signaling. These findings have contributed to our understanding of the early steps of chitin signaling. This review focuses on current knowledge about CERK1-mediated receptor complex formation and subsequent intracellular signaling.

AB - Lysin motif (LysM) receptor-like proteins/kinases (LysM-RLPs/RLKs) are well known to play an important role in the induction of defense or symbiosis signaling through the recognition of carbohydrate ligands in plants. Chitin elicitor receptor kinase 1 (CERK1) is the receptor-like kinase (RLK) essential for chitin-induced defense signaling in Arabidopsis and rice. At/OsCERK1 is also known to be important for peptidoglycan (PGN)-induced defense signaling. To induce chitin and PGN responses, CERK1 forms a receptor complex with corresponding LysM-type receptors such as CEBiP, LYM1/3 or LYP4/6. Furthermore, OsCERK1 in rice also plays a key role in lipopolysaccharide (LPS) signaling, and AtCERK1 in Arabidopsis is involved in unbranched β-glucan signaling. In any case, CERK1 plays a crucial role in the activation of defense signaling by these ligands and is an essential hub-RLK/co-receptor in these systems. After chitin perception, autophosphorylation of the CERK1 kinase domain is essential for inducing immune signaling, and some functionally important phosphorylation sites have been identified. In addition, several CERK1-interacting proteins and their contribution to the downstream signaling have been reported. In particular, phosphorylation of receptor-like cytoplasmic kinases (RLCKs) by CERK1 is important for the activation of chitin signaling. These findings have contributed to our understanding of the early steps of chitin signaling. This review focuses on current knowledge about CERK1-mediated receptor complex formation and subsequent intracellular signaling.

KW - CEBiP

KW - CERK1

KW - Chitin

KW - Lysin motif (LysM)

KW - Plant U-box protein (PUB)

KW - Receptor-like cytoplasmic kinase (RLCK)

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U2 - 10.1007/s10327-018-0828-x

DO - 10.1007/s10327-018-0828-x

M3 - Review article

AN - SCOPUS:85056339651

VL - 85

JO - Journal of General Plant Pathology

JF - Journal of General Plant Pathology

SN - 1345-2630

IS - 1

ER -