Irreversible Effects of Diethylstilbestrol on Reproductive Organs and a Current Approach for Epigenetic Effects of Endocrine Disrupting Chemicals

Shinichi Miyagawa, Ryohei Yatsu, Tamotsu Sudo, Katsuhide Igarashi, Jun Kanno, Taisen Iguchi

Research output: Chapter in Book/Report/Conference proceedingChapter

Original languageEnglish
Title of host publicationToxicology and Epigenetics
PublisherJohn Wiley and Sons
Pages357-364
Number of pages8
ISBN (Print)9781119976097
DOIs
Publication statusPublished - 8 Aug 2012

Keywords

  • Bisulfite sequence, for CpG simultaneous examination
  • DES exposure in neonatal, and gene misexpression in adulthood
  • DNA methylation, transgenerational effects, EDCs on pathway
  • DOHaD, a DES, on reproductive/cancer, adipogenesis and obesity
  • DOHaD/FOAD paradigm, EDCs on human/animal health
  • EDCs, deleteriously modifying gene expression, and disruption
  • Irreversible effects of DES on reproductive, approach for EDC
  • Receptor-based assays, biological activity of chemicals

Cite this

Miyagawa, S., Yatsu, R., Sudo, T., Igarashi, K., Kanno, J., & Iguchi, T. (2012). Irreversible Effects of Diethylstilbestrol on Reproductive Organs and a Current Approach for Epigenetic Effects of Endocrine Disrupting Chemicals. In Toxicology and Epigenetics (pp. 357-364). John Wiley and Sons. https://doi.org/10.1002/9781118349045.ch18