Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains

Aya Mizutani; Akihiko Kikuchi; Jun Kobayashi; Yoshikatsu Akiyama; Hideko Kanazawa; Teruo Okano

Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains

Aya Mizutani, Akihiko Kikuchi, Jun Kobayashi, Yoshikatsu Akiyama, Hideko Kanazawa, Teruo Okano

Department of Materials Science and Technology

Research output: Contribution to conference › Paper › peer-review

Abstract

In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.

Original language	English
Pages	2037
Number of pages	1
Publication status	Published - 2006
Event	55th SPSJ Annual Meeting - Nagoya, Japan Duration: 24 May 2006 → 26 May 2006

Conference

Conference	55th SPSJ Annual Meeting
Country/Territory	Japan
City	Nagoya
Period	24/05/06 → 26/05/06

Keywords

Cell adhesion
High-density polymer grafted surfaces
Poly(N-isopropylacrylamide)
Surface-initiated atom transfer radical polymerization
Thermoresponsive polymer

Cite this

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title = "Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains",

abstract = "In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.",

keywords = "Cell adhesion, High-density polymer grafted surfaces, Poly(N-isopropylacrylamide), Surface-initiated atom transfer radical polymerization, Thermoresponsive polymer",

author = "Aya Mizutani and Akihiko Kikuchi and Jun Kobayashi and Yoshikatsu Akiyama and Hideko Kanazawa and Teruo Okano",

year = "2006",

language = "English",

pages = "2037",

note = "55th SPSJ Annual Meeting ; Conference date: 24-05-2006 Through 26-05-2006",

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TY - CONF

T1 - Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains

AU - Mizutani, Aya

AU - Kikuchi, Akihiko

AU - Kobayashi, Jun

AU - Akiyama, Yoshikatsu

AU - Kanazawa, Hideko

AU - Okano, Teruo

PY - 2006

Y1 - 2006

N2 - In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.

AB - In the present research, thermoresponsive polymer brush surfaces grafted with high-density poly(N-isopropylacrylamide) (PIPAAm) are prepared by surface-initiated atom transfer radical polymerization (ATRP) using poly(p-chloromethylstyrene) as an ATRP initiator. Thermoresponsive surface characteristics are analyzed for the surfaces prepared at different reaction times. We succeeded to adhere endodermis cells (ECs) onto PIPAAm brush surfaces at 37°C while these cells detached by incubation at 20°C. Grafted polymer architecture as well as the grafted amount of PIPAAm chains should have important influence on cell adhesion/detachment behavior.

KW - Cell adhesion

KW - High-density polymer grafted surfaces

KW - Poly(N-isopropylacrylamide)

KW - Surface-initiated atom transfer radical polymerization

KW - Thermoresponsive polymer

UR - http://www.scopus.com/inward/record.url?scp=33749821291&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33749821291

SP - 2037

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Interfacial characterization of thermoresponsive surfaces grafted with high-density polymer chains

Abstract

Conference

Keywords

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