TY - JOUR
T1 - Histone Modification-Dependent Transcriptional Regulation of Defence Genes in Early Response of Arabidopsis to Spodoptera litura Attack
AU - Yusuf, Ahmed
AU - Wakaya, Kota
AU - Sakamoto, Takuya
AU - Uemura, Takuya
AU - Okamura, Koudai
AU - Ramadan, Abdelaziz
AU - Nozawa, Akira
AU - Suzuki, Takamasa
AU - Inui, Yayoi
AU - Matsunaga, Sachihiro
AU - Sawasaki, Tatsuya
AU - Arimura, Gen Ichiro
N1 - Publisher Copyright:
© 2024 The Author(s). Plant, Cell & Environment published by John Wiley & Sons Ltd.
PY - 2024
Y1 - 2024
N2 - Histone modification is a cellular process for transcriptional regulation. In herbivore-damaged plants, activation of genes involved in defence responses is required for antiherbivore properties, but little is known about how the chromatin remodelling system is involved. In Arabidopsis (Arabidopsis thaliana) plants responding to Spodoptera litura larvae, HAC1 and HDA6, a histone acetyltransferase and a histone deacetylase, respectively, were found here to be involved in histone H3 (Lys9; H3K9) acetylation/deacetylation at the promoter region of the plant defensin gene PDF1.2 and the gene body of ethylene response factor 13 (ERF13) as early as 2 h after the onset of herbivore attack. The H3K9 acetylation was responsible for the robust upregulation of PDF1.2 later, at 24 h, and ERF13 even earlier, at 1 h. TOPLESS (TPL) and TOPLESS-related (TPR) corepressors interacted with HDA6 to deacetylate H3K9 at PDF1.2 and ERF13, while negatively regulating the expression of PDF1.2 but not ERF13. Furthermore, TPL also interacted with ERF13, resulting in ERF13-mediated regulation of PDF1.2. Taken together, these data suggest a model of promoter-restricted, TPL/TPR-directed histone deacetylation and transcription factor repression in healthy Arabidopsis plants for the feedback regulation of the antiherbivore response.
AB - Histone modification is a cellular process for transcriptional regulation. In herbivore-damaged plants, activation of genes involved in defence responses is required for antiherbivore properties, but little is known about how the chromatin remodelling system is involved. In Arabidopsis (Arabidopsis thaliana) plants responding to Spodoptera litura larvae, HAC1 and HDA6, a histone acetyltransferase and a histone deacetylase, respectively, were found here to be involved in histone H3 (Lys9; H3K9) acetylation/deacetylation at the promoter region of the plant defensin gene PDF1.2 and the gene body of ethylene response factor 13 (ERF13) as early as 2 h after the onset of herbivore attack. The H3K9 acetylation was responsible for the robust upregulation of PDF1.2 later, at 24 h, and ERF13 even earlier, at 1 h. TOPLESS (TPL) and TOPLESS-related (TPR) corepressors interacted with HDA6 to deacetylate H3K9 at PDF1.2 and ERF13, while negatively regulating the expression of PDF1.2 but not ERF13. Furthermore, TPL also interacted with ERF13, resulting in ERF13-mediated regulation of PDF1.2. Taken together, these data suggest a model of promoter-restricted, TPL/TPR-directed histone deacetylation and transcription factor repression in healthy Arabidopsis plants for the feedback regulation of the antiherbivore response.
KW - Arabidopsis thaliana
KW - Spodoptera litura
KW - TOPLESS (TPL) and TOPLESS-related (TPR) corepressors
KW - histone acetyltransferase of the CBP family 1 (HAC1)
KW - histone deacetylase 6 (HDA6)
UR - http://www.scopus.com/inward/record.url?scp=85212983001&partnerID=8YFLogxK
U2 - 10.1111/pce.15345
DO - 10.1111/pce.15345
M3 - Article
AN - SCOPUS:85212983001
SN - 0140-7791
JO - Plant, Cell and Environment
JF - Plant, Cell and Environment
ER -