FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians

D. P. Potaczek; M. Sanak; C. Nishiyama; K. Okumura; H. Ogawa; A. Szczeklik

doi:10.1111/j.1744-313X.2008.00784.x

FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians

D. P. Potaczek, M. Sanak, C. Nishiyama, K. Okumura, H. Ogawa, A. Szczeklik

Department of Biological Science and Technology

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

Two FCER1A gene proximal promoter polymorphisms, -344C > T and -95T > C, both associated with total serum IgE and/or allergic disorders in Caucasians and East Asians, were shown to influence the gene expression in additive manner. In face of the rarity of other proximal promoter variants in Caucasians or their lack in East Asians, future investigations of the FCER1A locus in these ethnic groups should probably focus on three common haplotypes of the common -344C > T and -95T > C polymorphisms.

Original language	English
Pages (from-to)	339-340
Number of pages	2
Journal	International Journal of Immunogenetics
Volume	35
Issue number	4-5
DOIs	https://doi.org/10.1111/j.1744-313X.2008.00784.x
Publication status	Published - Aug 2008

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title = "FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians",

abstract = "Two FCER1A gene proximal promoter polymorphisms, -344C > T and -95T > C, both associated with total serum IgE and/or allergic disorders in Caucasians and East Asians, were shown to influence the gene expression in additive manner. In face of the rarity of other proximal promoter variants in Caucasians or their lack in East Asians, future investigations of the FCER1A locus in these ethnic groups should probably focus on three common haplotypes of the common -344C > T and -95T > C polymorphisms.",

author = "Potaczek, {D. P.} and M. Sanak and C. Nishiyama and K. Okumura and H. Ogawa and A. Szczeklik",

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language = "English",

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journal = "International Journal of Immunogenetics",

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T1 - FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians

AU - Potaczek, D. P.

AU - Sanak, M.

AU - Nishiyama, C.

AU - Okumura, K.

AU - Ogawa, H.

AU - Szczeklik, A.

PY - 2008/8

Y1 - 2008/8

N2 - Two FCER1A gene proximal promoter polymorphisms, -344C > T and -95T > C, both associated with total serum IgE and/or allergic disorders in Caucasians and East Asians, were shown to influence the gene expression in additive manner. In face of the rarity of other proximal promoter variants in Caucasians or their lack in East Asians, future investigations of the FCER1A locus in these ethnic groups should probably focus on three common haplotypes of the common -344C > T and -95T > C polymorphisms.

AB - Two FCER1A gene proximal promoter polymorphisms, -344C > T and -95T > C, both associated with total serum IgE and/or allergic disorders in Caucasians and East Asians, were shown to influence the gene expression in additive manner. In face of the rarity of other proximal promoter variants in Caucasians or their lack in East Asians, future investigations of the FCER1A locus in these ethnic groups should probably focus on three common haplotypes of the common -344C > T and -95T > C polymorphisms.

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U2 - 10.1111/j.1744-313X.2008.00784.x

DO - 10.1111/j.1744-313X.2008.00784.x

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AN - SCOPUS:52649117506

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VL - 35

SP - 339

EP - 340

JO - International Journal of Immunogenetics

JF - International Journal of Immunogenetics

IS - 4-5

ER -

FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians

Abstract

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