Dynamic Interconversion between Boroxine Cages Based on Pyridine Ligation

Kosuke Ono, Shunsuke Shimo, Kohei Takahashi, Nobuhiro Yasuda, Hidehiro Uekusa, Nobuharu Iwasawa

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6 Citations (Scopus)


Dynamic interconversion between large covalent organic cages was achieved simply by heating or acid/base treatment. A mixture of the boroxine cages 12-mer and 15-mer was cleanly converted into a pyridine adduct of the 9-mer boroxine cage upon treatment with pyridine, and the geometry of N-coordinated boron atoms changed from trigonal to tetrahedral. The reverse reaction was achieved by heating or acid treatment. In this process, the larger boroxine cages 12-mer and 15-mer were found to be entropically favored owing to the release of free pyridine molecules from 9-mer⋅6 Py.

Original languageEnglish
Pages (from-to)3113-3117
Number of pages5
JournalAngewandte Chemie - International Edition
Issue number12
Publication statusPublished - 12 Mar 2018


  • boroxines
  • covalent organic cages
  • dynamic interconversion
  • supramolecular chemistry

Cite this

Ono, K., Shimo, S., Takahashi, K., Yasuda, N., Uekusa, H., & Iwasawa, N. (2018). Dynamic Interconversion between Boroxine Cages Based on Pyridine Ligation. Angewandte Chemie - International Edition, 57(12), 3113-3117. https://doi.org/10.1002/anie.201713221