Abstract
The hepatocyte spheroid array was prepared by endothelial-hepatocyte co-culture on the poly(ethylene glycol) (PEG) brush surface micropatterned with plasma etch. Cell adherent domain sizes and their distances were important for effective spheroid formation. Live-dead staining and fluorescence immunohistochemistry revealed that hepatocyte spheroids underlaid with endothelial cells kept high viability and well-maintained hepatocyte specific function for long period.
| Original language | English |
|---|---|
| Article number | F5.2 |
| Pages (from-to) | 43-45 |
| Number of pages | 3 |
| Journal | Materials Research Society Symposium Proceedings |
| Volume | EXS |
| Issue number | 1 |
| Publication status | Published - 1 Dec 2004 |
| Event | 2003 MRS Fall Meeting - Boston, MA, United States Duration: 1 Dec 2003 → 4 Dec 2003 |