Convectional drug release using fast deswelling response of comb-type grafted poly(N-isopropylacrylamide) hydrogels

Y. Kaneko, K. Sakai, A. Kikuchi, T. Aoyagi, Y. Sakurai, T. Okano

Research output: Contribution to conferencePaperpeer-review

Abstract

Conventional drug transport was demonstrated using rapid deswelling of graft-type gels. A novel releasing mechanism was designed for therapeutic systems using the gels as pumping matrix. A sharp and larger drug release rate was observed, followed by release after 25 minutes. The drug was released after convectional water outflow, and almost all drug incorporated within the gel was released due to this rapid convectional transport.

Original languageEnglish
Pages467
Number of pages1
Publication statusPublished - 1996
EventProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2) - Toronto, Can
Duration: 29 May 19962 Jun 1996

Conference

ConferenceProceedings of the 1996 5th World Biomaterials Congress. Part 2 (of 2)
CityToronto, Can
Period29/05/962/06/96

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