Cell patterning using hydrophilic micropatterned interfaces for tissue engineering application

Yukiko Tsuda, Akihiko Kikuchi, Jun Kobayashi, Masayuki Yamato, Guoping Chen, Teruo Okano

Research output: Contribution to conferencePaperpeer-review

Abstract

Hydrophilic polyacrylamide (PAAm) was grafted onto silanized glass surfaces with regulated patterns utilizing a remodelled LCD projector and photolithography technique. PAAm pattern formation was confirmed by adsorption of FITC- labeled BSA. Endothelial cells adhered and extended in oriented shape only onto 10 or 20-μm width of silanized glass domains but not onto hydrophilic PAAm domains, indicating successful and selective cell adhesion.

Original languageEnglish
Pages5225-5226
Number of pages2
Publication statusPublished - 2005
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: 20 Sept 200522 Sept 2005

Conference

Conference54th SPSJ Symposium on Macromolecules
Country/TerritoryJapan
CityYamagata
Period20/09/0522/09/05

Keywords

  • Cell orientation
  • LCD projector
  • Micropatterned surface
  • Photolithography
  • Polyacrylamide

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