Asymmetric Autocatalysis Initiated by Crystal Chirality of Achiral Compounds

Arimasa Matsumoto, Yoshiyasu Kaimori, Tsuneomi Kawasaki, Kenso Soai

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Chiral crystallization of achiral compounds is attracting much attention, especially in areas of chirality research such as chiral separation and generation. Spontaneous chiral crystallization generates chirality and is a possible origin of homochirality. Although various organic and inorganic achiral compounds form chiral crystals, there are few examples of the use of this chirality for the control of enantioselective reactions of organic compounds. In this chapter, we describe how asymmetric autocatalysis can successfully utilize crystal chirality of achiral organic compounds to afford highly enantioenriched products with the absolute structure corresponding to the chirality of the crystals used.

Original languageEnglish
Title of host publicationAdvances in Asymmetric Autocatalysis and Related Topics
PublisherElsevier
Pages337-355
Number of pages19
ISBN (Electronic)9780128128251
ISBN (Print)9780128128244
DOIs
Publication statusPublished - 23 May 2017

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Keywords

  • Amplification of ee
  • Asymmetric autocatalysis
  • Chiral crystal
  • Chirality

Cite this

Matsumoto, A., Kaimori, Y., Kawasaki, T., & Soai, K. (2017). Asymmetric Autocatalysis Initiated by Crystal Chirality of Achiral Compounds. In Advances in Asymmetric Autocatalysis and Related Topics (pp. 337-355). Elsevier. https://doi.org/10.1016/B978-0-12-812824-4.00018-6