Assembled catalysts of titanium and non-cross-linked chiral copolymers for an enantioselective carbonyl-ene reaction

Yoichi M.A. Yamada, Masato Ichinohe, Hideyo Takahashi, Shiro Ikegami

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New insoluble chiral catalysts were prepared from a self-assembly of Ti(O-i-Pr)4 and non-cross-linked copolymers with (R)-binaphthol (BINOL) pendant groups. In the presence of one of the chiral catalysts, an enantioselective carbonyl-ene reaction proceeded at room temperature to give an adduct in 85% yield with 88% ee. This insoluble assembled catalyst was easily prepared and reusable.

Original languageEnglish
Pages (from-to)3431-3434
Number of pages4
JournalTetrahedron Letters
Issue number18
Publication statusPublished - 29 Apr 2002


  • Asymmetric reactions
  • Ene reactions
  • Polymer support
  • Self-assembly
  • Titanium and compounds

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