Approach for analysis of cardiomyocyte beating with cell array on ultrathin hydrophilic gel

Shintaroh Iwanaga; Yoshikatsu Akiyama; Akihiko Kikuchi; Masayuki Yamato; Kiyotaka Sakai; Teruo Okano

Approach for analysis of cardiomyocyte beating with cell array on ultrathin hydrophilic gel

Shintaroh Iwanaga, Yoshikatsu Akiyama, Akihiko Kikuchi, Masayuki Yamato, Kiyotaka Sakai, Teruo Okano

Department of Materials Science and Technology

Research output: Contribution to conference › Paper › peer-review

Abstract

It is important for analysis of re-constructed tissue to analyze cell functions. Techniques to control shape and size of culture areas and number of cells in culture areas are required for analysis of cell functions, because the control affects cell functions. We have succeeded in controlling number of cells with differentiation of patterned domain sizes. We found cardiomyocytes exhibited different beating rhythms between smaller and larger number of cells. Their beating of larger number was more stably and rhythmically. These results suggest number of cardiomyocytes affects their beatings. We will report the effect of cell number on cardiomyocyte beating.

Original language	English
Pages	4721-4722
Number of pages	2
Publication status	Published - 2005
Event	54th SPSJ Symposium on Macromolecules - Yamagata, Japan Duration: 20 Sept 2005 → 22 Sept 2005

Conference

Conference	54th SPSJ Symposium on Macromolecules
Country/Territory	Japan
City	Yamagata
Period	20/09/05 → 22/09/05

Keywords

Cardiomyocyte
Cell array
Collagen
Hydrophilic ultrathin polymer layer
Polyacrylamide
UV excimer laser

Cite this

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title = "Approach for analysis of cardiomyocyte beating with cell array on ultrathin hydrophilic gel",

abstract = "It is important for analysis of re-constructed tissue to analyze cell functions. Techniques to control shape and size of culture areas and number of cells in culture areas are required for analysis of cell functions, because the control affects cell functions. We have succeeded in controlling number of cells with differentiation of patterned domain sizes. We found cardiomyocytes exhibited different beating rhythms between smaller and larger number of cells. Their beating of larger number was more stably and rhythmically. These results suggest number of cardiomyocytes affects their beatings. We will report the effect of cell number on cardiomyocyte beating.",

keywords = "Cardiomyocyte, Cell array, Collagen, Hydrophilic ultrathin polymer layer, Polyacrylamide, UV excimer laser",

author = "Shintaroh Iwanaga and Yoshikatsu Akiyama and Akihiko Kikuchi and Masayuki Yamato and Kiyotaka Sakai and Teruo Okano",

year = "2005",

language = "English",

pages = "4721--4722",

note = "54th SPSJ Symposium on Macromolecules ; Conference date: 20-09-2005 Through 22-09-2005",

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TY - CONF

T1 - Approach for analysis of cardiomyocyte beating with cell array on ultrathin hydrophilic gel

AU - Iwanaga, Shintaroh

AU - Akiyama, Yoshikatsu

AU - Kikuchi, Akihiko

AU - Yamato, Masayuki

AU - Sakai, Kiyotaka

AU - Okano, Teruo

PY - 2005

Y1 - 2005

N2 - It is important for analysis of re-constructed tissue to analyze cell functions. Techniques to control shape and size of culture areas and number of cells in culture areas are required for analysis of cell functions, because the control affects cell functions. We have succeeded in controlling number of cells with differentiation of patterned domain sizes. We found cardiomyocytes exhibited different beating rhythms between smaller and larger number of cells. Their beating of larger number was more stably and rhythmically. These results suggest number of cardiomyocytes affects their beatings. We will report the effect of cell number on cardiomyocyte beating.

AB - It is important for analysis of re-constructed tissue to analyze cell functions. Techniques to control shape and size of culture areas and number of cells in culture areas are required for analysis of cell functions, because the control affects cell functions. We have succeeded in controlling number of cells with differentiation of patterned domain sizes. We found cardiomyocytes exhibited different beating rhythms between smaller and larger number of cells. Their beating of larger number was more stably and rhythmically. These results suggest number of cardiomyocytes affects their beatings. We will report the effect of cell number on cardiomyocyte beating.

KW - Cardiomyocyte

KW - Cell array

KW - Collagen

KW - Hydrophilic ultrathin polymer layer

KW - Polyacrylamide

KW - UV excimer laser

UR - http://www.scopus.com/inward/record.url?scp=33645582892&partnerID=8YFLogxK

M3 - Paper

AN - SCOPUS:33645582892

SP - 4721

EP - 4722

T2 - 54th SPSJ Symposium on Macromolecules

Y2 - 20 September 2005 through 22 September 2005

ER -

Approach for analysis of cardiomyocyte beating with cell array on ultrathin hydrophilic gel

Abstract

Conference

Keywords

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