Reflectance on an optical lens surface changes its optical characteristics. To overcome this problem, an antireflection structure (ARS) was used to prevent reflection. The resin used in previous studies was not satisfactory for the optical device, and therefore in this study, a newly developed resin was used to fabricate an optical lens with antifouling property. Experimental results showed that the fabricated optical lens exhibited an antifouling property with a higher water contact angle and a lower slip drop angle compared to those of the non-fabricated optical lens. It was also found that there was no change in the shape and reflectance of the lens even after wiping 25 times in a wiping test. Furthermore, the result of the measurement the full width at 1/e 2 of peak indicated that the fabricated lens and the non-ARS lens showed similar optical performance.