Fingerprint Dive into the research topics where Research Institute for Biomedical Sciences is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Interleukin-1 Medicine & Life Sciences
T-Lymphocytes Medicine & Life Sciences
Interleukin-17 Medicine & Life Sciences
Interleukin-8 Medicine & Life Sciences
Cytokines Medicine & Life Sciences
B-Lymphocytes Medicine & Life Sciences
Genes Medicine & Life Sciences
Dendritic Cells Medicine & Life Sciences

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Research Output 1972 2019

1.自然免疫と獲得免疫のインターフェース

Translated title of the contribution: Interface between innate and adaptive immunityKubo, M., 1 Jan 2019, In : Japanese Journal of Allergology. 68, 3, p. 132-137 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A dendritic cell-based systemic vaccine induces long-lived lung-resident memory Th17 cells and ameliorates pulmonary mycosis

Ueno, K., Urai, M., Sadamoto, S., Shinozaki, M., Takatsuka, S., Abe, M., Otani, Y., Yanagihara, N., Shimizu, K., Iwakura, Y., Shibuya, K., Miyazaki, Y. & Kinjo, Y., 1 Jan 2019, In : Mucosal Immunology. 12, 1, p. 265-276 12 p.

Research output: Contribution to journalArticle

Th17 Cells
Mycoses
Dendritic Cells
Vaccines
Cryptococcus gattii

AIM2 inflammasome-derived IL-1β induces postoperative ileus in mice

Hupa, K. J., Stein, K., Schneider, R., Lysson, M., Schneiker, B., Hornung, V., Latz, E., Iwakura, Y., Kalff, J. C. & Wehner, S., 1 Dec 2019, In : Scientific reports. 9, 1, 10602.

Research output: Contribution to journalArticle

Open Access
Inflammasomes
Ileus
Interleukin-1
Melanoma
Microbiota
2 Citations (Scopus)

Anti-tumor effects of mAb against l-type amino acid transporter 1 (LAT1) bound to human and monkey LAT1 with dual avidity modes

Ueda, S., Hayashi, H., Miyamoto, T., Abe, S., Hirai, K., Matsukura, K., Yagi, H., Hara, Y., Yoshida, K., Okazaki, S., Tamura, M., Abe, Y., Agatsuma, T., Niwa, S. I., Masuko, K. & Masuko, T., 1 Feb 2019, In : Cancer Science. 110, 2, p. 674-685 12 p.

Research output: Contribution to journalArticle

Open Access
Amino Acid Transport Systems
Haplorhini
Neoplasms
Macaca
Macaca fascicularis
7 Citations (Scopus)

CARD9 + microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment

Drummond, R. A., Swamydas, M., Oikonomou, V., Zhai, B., Dambuza, I. M., Schaefer, B. C., Bohrer, A. C., Mayer-Barber, K. D., Lira, S. A., Iwakura, Y., Filler, S. G., Brown, G. D., Hube, B., Naglik, J. R., Hohl, T. M. & Lionakis, M. S., 1 May 2019, In : Nature Immunology. 20, 5, p. 559-570 12 p.

Research output: Contribution to journalArticle

Neutrophil Infiltration
Microglia
Interleukin-1
Immunity
Central Nervous System

CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis

Blanco-Pérez, F., Kato, Y., Gonzalez-Menendez, I., Laiño, J., Ohbayashi, M., Burggraf, M., Krause, M., Kirberg, J., Iwakura, Y., Martella, M., Quintanilla-Martinez, L., Shibata, N., Vieths, S., Scheurer, S. & Toda, M., 3 Jul 2019, In : Scientific reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Enteritis
Eosinophils
Neutrophils
Egg White
Jejunum

Cell-free DNA in blood circulation is generated by DNase1L3 and caspase-activated DNase

Watanabe, T., Takada, S. & Mizuta, R., 27 Aug 2019, In : Biochemical and Biophysical Research Communications. 516, 3, p. 790-795 6 p.

Research output: Contribution to journalArticle

Blood Circulation
Hemodynamics
DNA
Tumors
Hepatocytes

Combined treatment with HMGN1 and anti-CD4 depleting antibody reverses T cell exhaustion and exerts robust anti-tumor effects in mice

Chen, C. Y., Ueha, S., Ishiwata, Y., Yokochi, S., Yang, D., Oppenheim, J. J., Ogiwara, H., Shichino, S., Deshimaru, S., Shand, F. H. W., Shibayama, S. & Matsushima, K., 29 Jan 2019, In : Journal for ImmunoTherapy of Cancer. 7, 1, 21.

Research output: Contribution to journalArticle

Open Access
HMGN1 Protein
T-Lymphocytes
Antibodies
Neoplasms
Nucleosomes

Cutaneous p38 mitogen-activated protein kinase activation triggers psoriatic dermatitis

Sakurai, K., Dainichi, T., Garcet, S., Tsuchiya, S., Yamamoto, Y., Kitoh, A., Honda, T., Nomura, T., Egawa, G., Otsuka, A., Nakajima, S., Matsumoto, R., Nakano, Y., Otsuka, M., Iwakura, Y., Grinberg-Bleyer, Y., Ghosh, S., Sugimoto, Y., Guttman-Yassky, E., Krueger, J. G. & 1 others, Kabashima, K., Oct 2019, In : Journal of Allergy and Clinical Immunology. 144, 4, p. 1036-1049 14 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Dermatitis
Psoriasis
Skin
Anisomycin